ggPMX: 'ggplot2' Based Tool to Facilitate Diagnostic Plots for NLME Models

At Novartis, we aimed at standardizing the set of diagnostic plots used for modeling activities in order to reduce the overall effort required for generating such plots. For this, we developed a guidance that proposes an adequate set of diagnostics and a toolbox, called 'ggPMX' to execute them. 'ggPMX' is a toolbox that can generate all diagnostic plots at a quality sufficient for publication and submissions using few lines of code. This package focuses on plots recommended by ISoP <doi:10.1002/psp4.12161>. While not required, you can get/install the 'R' 'lixoftConnectors' package in the 'Monolix' installation, as described at the following url <>. When 'lixoftConnectors' is available, 'R' can use 'Monolix' directly to create the required Chart Data instead of exporting it from the 'Monolix' gui.

Version: 1.2.11
Depends: R (≥ 3.5)
Imports: data.table, yaml, R6, gtable, ggplot2 (≥ 3.4.0), ggforce, magrittr, stringr, assertthat, GGally, zoo, knitr, rmarkdown, tidyr, dplyr, purrr, readr, rlang, checkmate, scales
Suggests: testthat, xtable, vdiffr, rxode2, nlmixr2, nlmixr2data, lixoftConnectors, xgxr, withr, lifecycle
Published: 2023-11-30
DOI: 10.32614/CRAN.package.ggPMX
Author: Amine Gassem [aut], Bruno Bieth [aut], Irina Baltcheva [aut], Thomas Dumortier [aut], Christian Bartels [aut], Souvik Bhattacharya [aut], Inga Ludwig [aut], Ines Paule [aut], Didier Renard [aut], Matthew Fidler ORCID iD [aut, cre], Seid Hamzic [aut], Benjamin Guiastrennec [ctb], Kyle T Baron ORCID iD [ctb], Qing Xi Ooi [ctb], Novartis Pharma AG [cph]
Maintainer: Matthew Fidler <matt.fidler at>
License: GPL-2
NeedsCompilation: no
Materials: README NEWS
CRAN checks: ggPMX results


Reference manual: ggPMX.pdf
Vignettes: ggPMX: User guide


Package source: ggPMX_1.2.11.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): ggPMX_1.2.11.tgz, r-oldrel (arm64): ggPMX_1.2.11.tgz, r-release (x86_64): ggPMX_1.2.11.tgz, r-oldrel (x86_64): ggPMX_1.2.11.tgz
Old sources: ggPMX archive

Reverse dependencies:

Reverse suggests: nlmixr2rpt


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